CVD-100 Vacuum Freeze Dryer | 1㎡ Shelf Area · 8~12kg per Batch · 8 Shelves

CVD-100 vacuum freeze dryer has a shelf area of 1㎡, 8 shelf layers, a batch load of 812kg, a cold trap temperature of -45-65℃, and a complete freeze-drying cycle of about 18~27 hours. After the material is frozen in the chamber to below the eutectic point, ice directly sublimates into water vapor under a vacuum environment of ≤15Pa, and is captured by the cold trap through desublimation—this is the equipment tier that scales laboratory formulas up to small-batch production.

Where it is used

Loading capacity is calculated at a tray loading density of 8~12 kg/㎡. Actual loading depends on material density, cutting thickness, and tray spreading method. For small specifications, see the vacuum freeze dryer series page.

How drying works

The cold trap (water vapor trap) operates at -45~-65℃ and is installed at the rear of the drying chamber. The internal coil and refrigeration unit form a refrigeration cycle. Its role is to desublimate water vapor into frost before it enters the vacuum pump, protecting the vacuum pump from water vapor while continuously removing the sublimated water vapor from the chamber.

Technical parameters

Quick specifications

Full parameters

Main configuration list

Why choose it

• The dividing point from laboratory to small-batch production. 8 shelf layers, 812kg batch load, running one to two batches a day gives 824kg of finished product, enough for small-batch market validation and enough to send samples to customers.
• Shelf area determines loading capacity, not the bigger the better. 1㎡ corresponds to 812kg loading, with exactly the same process parameters as the 0.4㎡ entry model (-55120℃ shelf, -45~-65℃ cold trap), so curves can be carried over directly during scale-up.
• A complete set of freeze-drying conditions. Refrigeration system, Roots + rotary vane vacuum unit, silicone oil circulation heating, and PLC curve control are all on the same machine, with no need for an additional freezer for pre-freezing.
• Low cost for changing products. Tray size and shelf layers are fixed; changing materials only requires changing the spreading method and freeze-drying curve, with no changes to the production line or equipment.

FAQ

How much can 1㎡ of shelf hold at once, and how much can it output?

Batch capacity is 10kg, with a loading range of 812kg, calculated at a loading density of 812kg per square meter of tray area. Finished product weight depends on the material’s initial moisture content and target moisture content, and is not the same number as the loading weight. To calculate loading capacity for a specific material, you can contact us with the material name, batch loading weight, and moisture content.

How is a freeze-drying cycle of about 24 hours derived?

Pre-freezing 35 hours, sublimation drying 1216 hours, desorption drying 36 hours, totaling 1827 hours across the three stages. The design summary table records the processing time for this specification as 24 hours. Actual duration is affected by material thickness, moisture content, spreading density, and target moisture content; thick-cut or high-moisture materials tend toward the upper limit.

Why is a Roots pump needed, can a rotary vane pump alone work?

The Roots pump is a booster pump and cannot start alone. The backing rotary vane pump first evacuates the chamber below 1 kPa, then the Roots pump automatically engages. During the sublimation stage, a large amount of water vapor is generated; insufficient pumping speed will slow the drying rate, so when the freeze-drying target is ≤15Pa, the unit must include a Roots pump. For freeze-drying process parameters and eutectic point data, see the technical library.

How is the shelf temperature of -55℃ to +120℃ used?

In the pre-freezing stage, the refrigeration system pulls the shelves to the low-temperature side to freeze the material below the eutectic point; in the sublimation stage, it adjusts upward to around +60℃ to supply heat so ice continues to sublimate; in the desorption stage, it rises further to +60~+120℃ to remove bound water. The entire process is programmed in stages on the touch screen according to the curve, with temperature control accuracy of ±1℃.

What is the difference between CVD-100 and CVD-500?

The difference is in shelf area and output scale. CVD-100 is 1㎡, 8 shelf layers, 812kg per batch; CVD-500 is 5㎡, 12 shelf layers, 4060kg per batch. The process parameters are the same; selection depends on batch loading weight and whether continuous discharge is needed: choose CVD-100 for around 10kg per day, choose CVD-500 for around 50kg per day.

To calculate loading capacity, freeze-drying curves, or cold trap configuration for a specific material, provide the material name, batch loading weight, and moisture content, and engineers will provide a selection plan.